The veterinary clinical studies allow the assessment of pharmacological or biological products under field conditions. The wide networking farms allow having a range of candidate farms to select the optimal experimental site in each case, depending on the target pathology of the product.
The main controls in these studies, in addition to the controls detailed in the zootechnical studies, are:
- Individual clinical scoring: adapted to each type of study: Assessment of specific clinical signs (respiratory, digestive, cutaneous, nervous, presence of mastitis + metritis, etc).
- Individual record of body temperature and its evolution in time.
- Sampling of all type of samples, depending on the pathology that is studied, mainly blood, milk, vaginal swab, tracheobronchial fluid, etc.
- If required, sacrifice of animals and later necropsy and sampling of organs and tissues.
In general these are controls and samplings adapted to the experimental protocol requirements, very dependent on the pathology studied.
All these records and samplings are conducted following the Guidelines for good clinical practice (GCP). The statistical analysis of data and final report of the study are also conducted.